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 REEN Def Poster 11x16

The Clinical Evaluation Research Unit has received a grant worth $5.7 million over 5 years for the international, 60 Acute Care Unit (ICU/Burn Unit) RE-ENERGIZE RCT. The study will investigate the use of glutamine in 2700 patients with severe burn injuries and will evaluate clinical outcomes including mortality and morbidity as well as health related quality of life. Click here to read a local article regarding Dr. Heyland and CERU's acheivement. (NCT00985205)

Recruitment: Completed 

Status: Results Published at NEJM

Principal Investigator: Daren Heyland, MD, MSc

Funding Agency: Canadian Institutes of Health Research (CIHR)

NEJM Video


The RE-ENERGIZE Pilot Study

Canadian Principal Investigator: Domnique Garrel (University of Montreal)

US Principal Investigator: Paul Wischmeyer (University of Colorado)
Director, Clinical Evaluation Research Unit: Dr. Daren Heyland (Kingston General Hospital)

A pilot study had been completed that enrolled a total of 203 patients from 8 sites in the US and Canada over 3 years. The trial was funded by the American Burns Association/US Department of Defense and the Canadian Institutes of Heath Research and is registered at under the registration ID NCT00985205 and at under the registration ID ISRCTN92905442.


RE-ENERGIZE Related Articles

The RE-ENERGIZE Protocol - Download Full Article 

Re-energising burns research – Download Full Article




Volume Date
15 August 2018
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